Audio Summaries

  1. Issue Highlights - June 2020

    • Rapid Recurrence of Eosinophilic Esophagitis Activity After Successful Treatment in the Observation Phase of a Randomized Trial
    • Association Between Indefinite Dysplasia and Advanced Neoplasia in Patients With Inflammatory Bowel Diseases Undergoing Surveillance
    • Healthcare Costs of Patients With Biopsy-Confirmed Nonalcoholic Fatty Liver Disease Are Nearly Twice Those of Matched Controls
    • Significance of Liver Stiffness Changes on Magnetic Resonance Elastography In Primary Sclerosing Cholangitis
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  2. Issue Highlights - May 2020

    • Nutritional Risks in Adolescents After Bariatric Surgery
    • Gene Variants That Affects Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer
    • Stopping 5-ASA Therapy in Patients With Crohn’s Disease Starting Biologic Therapy Does Not Increase Risk of Adverse Outcomes
    • Including Relative Adrenal Insufficiency in the Definition and Classification of Acute-on-Chronic Liver Failure
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  3. Issue Highlights - April 2020

    • Clinical Factors Associated With Gastric Cancer in Individuals With Lynch Syndrome
    • Low Incidence of Aerodigestive Cancers In Patients With Negative Results From Colonoscopies, Regardless of Findings From Multitarget Stool DNA Tests
    • Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients With Nonalcoholic Fatty Liver Disease
    • Effects of Pancreatic Enzyme Replacement Therapy on Body Weight and Nutritional Assessments After Pancreatoduodenectomy in a Randomized Trial
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  4. Issue Highlights - March 2020

    • Monitoring a Combination of Calprotectin and Infliximab Identifies Patients with Mucosal Healing of Crohn’s Disease
    • Best Practices in Teaching Endoscopy Based on a Delphi Survey of Gastroenterology Program Directors and Endoscopy Education Experts in Endoscopy Education
    • Diagnostic Yield of One-Time Colonoscopy vs One-Time Flexible Sigmoidoscopy vs Multiple Rounds of Mailed Fecal Immunohistochemical Tests in Colorectal Cancer Screening
    • GALAD Score Detects Early Hepatocellular Carcinoma in an International Cohort of Patients with Nonalcoholic Steatohepatitis
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  5. Issue Highlights - February 2020

    • Optimizing Outcomes of Single-operator Cholangioscopy-guided Biopsies: Results of a Randomized Trial
    • Supplementary Anal Imaging by Magnetic Resonance Enterography in Patients With Crohn’s Disease Not Suspected of Having Perianal Fistulas
    • Efficacy of Epicutaneous Immunotherapy in Children With Milk-Induced Eosinophilic Esophagitis
    • Outcomes of Long-term Treatment of Chronic HBV Infection With Entecavir or Other Agents From a Randomized Trial in 24 Countries
    • Risk Of Gastrointestinal Bleeding Increases With Combinations Of Antithrombotic Agents And Patient Age
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  6. Issue Highlights - January 2020

    • Prevalence and Incidence of Intestinal Metaplasia and Dysplasia of Gastric Cardia in Barrett’s Esophagus After Endoscopic Therapy
    • Effects of Vedolizumab in Patients With Primary Sclerosing Cholangitis and Inflammatory Bowel Disease
    • Tofacitinib Treatment Is Associated With Modest and Reversible Increases in Serum Lipids in Patients With Ulcerative Colitis
    • Development and Validation of Hepamet Fibrosis Scoring System A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis
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  7. Issue Highlights - December 2019

    • Clinical and Molecular Features of Post-Colonoscopy Colorectal Cancers
    • Incidence of Immune-mediated Inflammatory Diseases Among Patients With Inflammatory Bowel Diseases in Denmark
    • Increased Risk of Death in First Year After Liver Transplantation Among Patients With Nonalcoholic Steatohepatitis vs Liver Disease of Other Etiologies
    • Daily Aspirin Use Associated With Reduced Risk for Fibrosis Progression in Patients With Nonalcoholic Fatty Liver Disease
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  8. Issue Highlights - October 2019

    • Efficacy of Pelvic Floor Muscle Training and Biofeedback vs Attention-control Treatment in Adults With Fecal Incontinence
    • Metachronous Neoplasias Arise in a Higher Proportion of Colon Segments From Which Large Polyps Were Previously Removed, and Can be Used to Estimate Incomplete Resection of 10–20 mm Colorectal Polyps
    • Prevalence and Risk Factors of Significant Fibrosis in Patients With Nonalcoholic Fatty Liver Without Steatohepatitis
    • Association between Renal Function Pattern and Mortality in Patients with Cirrhosis
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  9. Issue Highlights - September 2019

    • Clinical Characteristics and Outcomes of Patients With Postfundoplication Dysphagia
    • Prevalence of Germline Mutations in Polyposis and Colorectal Cancer-Associated Genes in Patients With Multiple Colorectal Polyps
    • Clopidogrel and Low-Dose Aspirin, Alone or Together, Reduce Risk of Colorectal Cancer
    • Health-related Quality of Life in Nonalcoholic Fatty Liver Disease Associates With Hepatic Inflammation
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  10. Issue Highlights - August 2019

    • Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases
    • Upfront Combination Therapy, Compared With Monotherapy for Patients Not Previously Treated With a Biologic Agent Associates With Reduced Risk of Inflammatory Bowel Disease-Related Complications in a Population-based Cohort Study
    • Statin Use Is Associated With Improved Outcomes of Patients With Primary Sclerosing Cholangitis
    • Cost Effectiveness of Hepatocellular Carcinoma Surveillance After a Sustained Virologic Response to Therapy in Patients With Hepatitis C Virus Infection and Advanced Fibrosis
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  11. Issue Highlights - July 2019

    • Combination Therapy With Infliximab and Azathioprine Improves Infliximab Pharmacokinetic Features and Efficacy: A Post Hoc Analysis
    • Safety of Tofacitinib for Treatment of Ulcerative Colitis, Based on 4.4 Years of Data From Global Clinical Trials
    • Effects of Alcohol Consumption and Metabolic Syndrome on Mortality in Patients With Nonalcoholic and Alcohol-Related Fatty Liver Disease
    • Preoperative Endoscopic Retrograde Cholangiopancreatography Is Not Associated With Increased Pancreatic Cancer Mortality
    • Association Between Endoscopist Personality and Rate of Adenoma Detection
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  12. Issue Highlights - June 2019

    • Rebleeding and Mortality After Lower Gastrointestinal Bleeding in Patients Taking Antiplatelets or Anticoagulants
    • Time to Colonoscopy and Risk of Colorectal Cancer in Patients With Positive Results From Fecal Immunochemical Tests
    • Efficacy of Live Attenuated Herpes Zoster Vaccine in Patients With Inflammatory Bowel Diseases
    • Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study
    • Barriers and Facilitators to Mediterranean Diet Adoption by Patients With Nonalcoholic Fatty Liver Disease in Northern Europe
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  13. Issue Highlights - May 2019

    • Accuracy of Noninvasive Scoring Systems in Assessing Risk of Death and Liver-Related Endpoints in Patients With Nonalcoholic Fatty Liver Disease
    • Most Patients With Gastroesophageal Reflux Disease Who Failed Proton Pump Inhibitor Therapy Have Functional Esophageal Disorders
    • Numbers and Features of Patients With a Diagnosis of Celiac Disease Without Duodenal Biopsy, Based on a National Survey
    • Clinical and Molecular Factors Associated With Histologic Response to Topical Steroids in Patients With Eosinophilic Esophagitis
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  14. Issue Highlights - April 2019

    • Progression of Barrett’s Esophagus to Malignancy
    • Low-Dose Aspirin and Gastrointestinal Bleeding
    • Functional Nausea and Vomiting Disorders in Adults
    • Cost Effectiveness of Universal Screening for Hepatitis C Virus
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  15. Issue Highlights - March 2019

    • Safety and Efficacy of Budesonide Oral Suspension Maintenance Therapy in Patients With Eosinophilic Esophagitis
    • Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients
    • Acceptability, Accuracy, and Safety of Disposable Transnasal Capsule Endoscopy for Barrett's Esophagus Screening
    • Normal Values of Esophageal Distensibility and Distension-Induced Contractility Measured by Functional Luminal Imaging Probe Panometry
    • Nonalcoholic Steatohepatitis is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates
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  16. Issue Highlights - February 2019

    • Previous Use of Antithrombotic Agents Reduces Mortality in Patients With High-risk Upper Gastrointestinal Bleeding
    • The Association Between Mutations in BRAF and Colorectal Cancer–Specific Survival Depends on Microsatellite Status and Tumor Stage
    • Patient-Reported Outcomes and Endoscopic Appearance of Ulcerative Colitis: A Systematic Review and Meta-Analysis
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  17. Issue Highlights - January 2019

    • New data shed little light on if screening individuals at high-risk for pancreatic cancer is effective and cost-effective in the long term.
    • Tofacitinib-induction therapy reduces symptoms within 3 days for patients with UC.
    • Vedolizumab is effective for adult UC patients who are anti-tumor necrosis factor naïve.
    • ESD is safer and more effective than esophagectomy for early-stage esophageal squamous cell carcinoma.
    • New findings show that endoscopic ultrasound accurately distinguishes celiac lymph nodes and celiac ganglia.
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  18. Issue Highlights - December 2018

    • Some medications for IBD increase risk for herpes zoster.
    • Nationwide study in Korea shows increase in risk of herpes zoster in patients with IBD, especially for those with ulcerative colitis.
    • New study shows long-term benefits of achieving maintained virologic response in patients with HBV, even after development of decompensated cirrhosis.
    • BMI is a significant predictor in discrepancy when assessing fibrosis in NAFLD with MRE vs. TE.
    • New study shows that restarting DOACs within 30 days doesn’t significantly increase risk of recurrent GI bleeding or reduce risk of thromboembolism.
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  19. Issue Highlights - November 2018

    • Endoscopist-related factors, rather than biology, are more likely to account for interval cancers in the proximal colon.
    • New data suggest that Crohn's patients have greater risk of high-risk HPV infection and thus may benefit from anal cancer screening.
    • New study on the factors associated with response to placebo in IBD patients has implications for clinical trial design.
    • Research finds an association between the grade of acute on chronic liver failure and response to terlipressin and albumin in hepatorenal syndrome.
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  20. Issue Highlights - October 2018

    • New study further suggests an association between IBD disease activity and cardiovascular risk.
    • Clinicians should consider screening for latent tuberculosis prior to the initiation of corticosteroids for IBD.
    • Diet and gut microbiota play an important role in CRC development, with low-inflammatory diets showing benefits.
    • Granulocyte colony stimulating factor with or without N-acetyl cysteine may be a safe and effective treatment for severe alcoholic hepatitis.
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