High Resolution Manometry in Scleroderma Patients

      We read with interest the article by Crowell et al
      • Crowell M.D.
      • et al.
      regarding the prevalence and type of esophageal motor abnormalities in systemic scleroderma patients. In that study, which involved 200 patients and 102 controls, the distinctive features of scleroderma esophagus (hypotensive esophagogastric junction pressure with absent contractility) were detected in only one third of patients. Moreover, the spectrum of esophageal motor abnormalities was heterogeneous, the most frequent finding being an absent contractility, as detected in 56%, followed by normal motility in 26%, and ineffective esophageal motility in 10% of patients. At multivariate logistic regression analysis, the predictors of severity esophageal dysmotility were disease duration, the total score on the Gastrointestinal Tract questionnaire, and the presence of interstitial lung disease.
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        • Crowell M.D.
        • et al.
        Clin Gastroenterol Hepatol. 2017; 15: 207-213

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