| Electronic Images of the Month |
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Hemobilia: A Rare Presentation of Acute Cholecystitis
A 75-year-old man was evaluated at the VA Caribbean Healthcare System's emergency room on August 2006 after he was brought in by his son. The patient was found at home lying on the floor, disoriented ...
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Dilka I. Gonzalez–Ortiz,
Doris H. Toro,
Wanda Vega
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Short communication
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pages e36-e37
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Double Pylorus: An Unusual Complication of Peptic Ulcer Disease (with video)
A 59-year-old man was admitted because of hematemesis and severe epigastric pain. He was in shock status on arrival in our hospital (systolic blood pressure, 65 mm Hg; pulse rate, 131 beats per minute...
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Chih–Wei Tseng,
Jai–Jen Tsai,
Hwai–Jeng Lin
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Short communication
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page e38
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Hepatocellular Carcinoma With Invasion Into Right Atrium
An 88-year-old male patient with a history of hypertensive cardiovascular disease, diabetes mellitus, and hyperlipidemia was admitted to the hospital because of chest pain, poor appetite, and body wei...
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Jai–Jen Tsai,
Chien–Wei Su,
Han–Chieh Lin
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Short communication
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pages e39-e40
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| CME Activities |
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Exam 1: Risk of Developing Proximal Versus Distal Colorectal Cancer After a Negative Colonoscopy: a Population Based Study
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Michael B. Fallon
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Examination
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pages 1063-1064
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Exam 2: Patients With Minimal Hepatic Encephalopathy Have Poor Insight Into Their Driving Skills
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Michael B. Fallon
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Examination
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page 1065
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| Abstracts From Around the World |
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Abstracts from Around the World
Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359:378–390.
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Discussion
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pages 1066-1067
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| Editorial |
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Realistic Expectations After Negative Colonoscopy
Gastroenterologists and the public have embraced the idea that colonoscopy can prevent most colorectal cancers. The idea was first proposed after the recognition that the majority of colorectal cancer...
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Robert S. Sandler
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Editorial
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pages 1068-1069
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| Review |
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Fluid Resuscitation in Acute Pancreatitis
11 July 2008
Acute pancreatitis is a common inflammatory disorder of the pancreas resulting in considerable morbidity and a mortality rate of approximately 5%. Although there are no pharmacologic treatments known ...
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Timothy B. Gardner,
Santhi Swaroop Vege,
Randall K. Pearson,
Suresh T. Chari
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Review article
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pages 1070-1076
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| Clinical Imaging |
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Imaging of Acute Pancreatitis and Its Complications
04 August 2008
Patients with acute pancreatitis may present with mild or severe disease, the latter comprising a minority of cases but accounting for most of the morbidity and mortality associated with this disease....
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Desiree E. Morgan
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Full-length article
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pages 1077-1085
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| Education Practice |
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Persistent Helicobacter pylori Infection After a Course of Antimicrobial Therapy—What's Next?
18 July 2008
A 35-year-old Hispanic woman with no significant past medical history presents to the emergency department at midnight with a 3-month history of intermittent epigastric pain culminating in 3 episodes ...
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Richard J. Saad,
William D. Chey
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Full-length article
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pages 1086-1090
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| Endoscopy Corner |
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Effect of a Time-Dependent Colonoscopic Withdrawal Protocol on Adenoma Detection During Screening Colonoscopy
18 July 2008
Background & Aims: Screening colonoscopy can prevent cancer by removal of adenomatous polyps. Recent evidence suggests that insufficient time for inspection during overly rapid colonoscope withdra...
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Robert L. Barclay,
Joseph J. Vicari,
Roger L. Greenlaw
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Full-length article
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pages 1091-1098
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| Original Articles-Alimentary Tract |
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Occurrence of Nighttime Gastroesophageal Reflux in Disturbed and Normal Sleepers
Background & Aims: It is not uncommon in a sleep laboratory to encounter individuals who have complaints of disturbed sleep, but who do not meet the criteria for a sleep disorder when evaluated by...
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William C. Orr,
Suanne Goodrich,
Paula Fernström,
Göran Hasselgren
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Full-length article
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pages 1099-1104
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Increased Immune Reactivity Predicts Aggressive Complicating Crohn's Disease in Children
11 July 2008
Background & Aims: The ability to identify children with CD who are at highest risk for rapid progression from uncomplicated to complicated phenotypes would be invaluable in guiding initial therap...
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Marla C. Dubinsky,
Subra Kugathasan,
Ling Mei,
Yoana Picornell,
Justin Nebel,
Iwona Wrobel,
Antonio Quiros,
Gary Silber,
Ghassan Wahbeh,
Lirona Katzir,
Eric Vasiliauskas,
Ron Bahar,
Anthony Otley,
David Mack,
Jonathan Evans,
Joel Rosh,
Maria Oliva Hemker,
Neal Leleiko,
Wallace Crandall,
Christine Langton,
Carol Landers,
Kent D. Taylor,
Stephan R. Targan,
Jerome I. Rotter,
James Markowitz,
Jeffrey Hyams,
Western Regional Pediatric IBD Research Alliance, Pediatric IBD Collaborative Research Group, and The Wisconsin Pediatric IBD Alliance
et al.
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Full-length article
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pages 1105-1111
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Cyclosporine and Infliximab as Rescue Therapy for Each Other in Patients With Steroid-Refractory Ulcerative Colitis
Background & Aims: In patients with severe corticosteroid-refractory ulcerative colitis, cyclosporine or infliximab may be added in an effort to induce remission. If the patient then fails either ...
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Elana A. Maser,
Deepthi Deconda,
Simon Lichtiger,
Thomas Ullman,
Daniel H. Present,
Asher Kornbluth
et al.
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Full-length article
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pages 1112-1116
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Risk of Developing Proximal Versus Distal Colorectal Cancer After a Negative Colonoscopy: A Population-Based Study
08 August 2008
Background & Aims: The incidence of colorectal cancer (CRC) overall is reduced for up to 10 years after a negative colonoscopy. The objective of this research was to determine the incidence of pro...
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Josh Lakoff,
Lawrence F. Paszat,
Refik Saskin,
Linda Rabeneck
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Full-length article
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pages 1117-1121
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Improved Diagnosis of Colorectal Cancer Using a Combination of Fecal Occult Blood and Novel Fecal Protein Markers
Background & Aims: Annual testing for fecal occult blood is recommended as first-line screening for the detection of colorectal cancer (CRC), but is affected by limited sensitivity. We initiated a...
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Johann Karl,
Norbert Wild,
Michael Tacke,
Herbert Andres,
Ursula Garczarek,
Wolfgang Rollinger,
Werner Zolg
et al.
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Full-length article
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pages 1122-1128
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| Original Articles-Liver, Pancreas, and Biliary Tract |
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Spleen Enlargement on Follow-Up Evaluation: A Noninvasive Predictor of Complications of Portal Hypertension in Cirrhosis
11 July 2008
Background & Aims: Splenomegaly is observed in most but not all patients with cirrhosis, and has been detected more often in patients showing complications of portal hypertension. We aimed to test...
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Annalisa Berzigotti,
Paola Zappoli,
Donatella Magalotti,
Carolina Tiani,
Valentina Rossi,
Marco Zoli
et al.
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Full-length article
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pages 1129-1134
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Patients With Minimal Hepatic Encephalopathy Have Poor Insight Into Their Driving Skills
Background & Aims: Minimal hepatic encephalopathy (MHE) is associated with impaired driving skills. It is not clear whether patients have insight into this. The Driving Behavior Survey (DBS) is a ...
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Jasmohan S. Bajaj,
Kia Saeian,
Muhammad Hafeezullah,
Raymond G. Hoffmann,
Thomas A. Hammeke
et al.
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Full-length article
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pages 1135-1139
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Evaluation of a Scoring System for Assessing Prognosis in Pediatric Acute Liver Failure
Background & Aims: Pediatric acute liver failure (PALF) results in death or need for liver transplantation (LT) in up to 50% of patients. A scoring system for predicting death or LT (Liver Injury ...
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Brandy R. Lu,
Jane Gralla,
Edwin Liu,
Emily L. Dobyns,
Michael R. Narkewicz,
Ronald J. Sokol
et al.
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Full-length article
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pages 1140-1145
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Race Is a Predictor of In-Hospital Mortality After Cholecystectomy, Especially in Those With Portal Hypertension
Background & Aims: Cholecystectomy is the most frequently performed gastrointestinal surgery in the United States. In this study, we characterized racial disparities in in-hospital mortality after...
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Geoffrey C. Nguyen,
Thomas A. Laveist,
Dorry L. Segev,
Paul J. Thuluvath
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Full-length article
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pages 1146-1154
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The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
18 July 2008
Background and Aims: Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic tumor with an innate resistance to therapy. Pancreatic stellate cells (PSCs) produce this excessively desmoplastic...
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Mert Erkan,
Christoph W. Michalski,
Simon Rieder,
Carolin Reiser–Erkan,
Ivane Abiatari,
Armin Kolb,
Nathalia A. Giese,
Irene Esposito,
Helmut Friess,
Jörg Kleeff
et al.
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Full-length article
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pages 1155-1161
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Diagnostic Ascertainment of Suspicious Pancreatic Mass: A Threshold Analysis
Background & Aims: It is frequently difficult to differentiate between a benign and malignant pancreatic mass. The aim of this study was to assess the parameters that affect the decision to perfor...
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Amnon Sonnenberg,
Sarah A. Rodriguez,
Douglas O. Faigel
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Full-length article
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pages 1162-1166
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| Brief Communications |
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Author(s) |
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Noncirrhotic Portal Hypertension in Patients With Human Immunodeficiency Virus–1 Infection
18 July 2008
Background & Aims: Noncirrhotic portal hypertension (NCPH) is unusual in North American patients. This study characterized patients with NCPH and human immunodeficiency virus–1 (HIV-1) infection t...
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Sophia Saifee,
Dean Joelson,
James Braude,
Roshan Shrestha,
Mark Johnson,
Marty Sellers,
Michael R. Galambos,
Raymond A. Rubin
et al.
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Full-length article
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pages 1167-1169
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High Prevalence of Functional Liver Derangement in Visceral Leishmaniasis at an Indian Tertiary Care Center
11 July 2008
Background & Aims: Functional derangement of liver in visceral leishmaniasis is reported infrequently in the literature. Because of this, many cases are wrongly diagnosed and treated as hepatitis....
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Purva Mathur,
Jyotish Chandra Samantaray,
Palash Samanta
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Full-length article
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pages 1170-1172
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| Letters to the Editor |
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Two-Step Approach for Diagnosing Celiac Disease
In their recent article (Clin Gastroenterol Hepatol 2008;6:314–320) Hopper et al found that adopting a 2-step approach by using IgA tissue transglutaminase (tTG) first and then IgA endomysial antibody...
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A. Bürgin–Wolff,
F. Hadziselimovic
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Correspondence
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page 1173
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Reply
We appreciate the comments of Dr Bürgin–Wolff and Prof Hadziselimovic. They raise 2 issues: firstly they demonstrate that the inclusion of immunoglobulin A (IgA) anti-gliadin antibodies (IgA-AGA) and ...
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Andrew D. Hopper,
David S. Sanders
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Correspondence
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pages 1173-1174
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Cover
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Miscellaneous
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page OFC
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| Frontmatter |
| Images of the Month |
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Article Title |
Author(s) |
Type |
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Cronkhite-Canada Syndrome: Panendoscopic Characterization With Esophagogastroduodenoscopy, Endoscopic Ultrasound, Colonoscopy, and Double Balloon Enteroscopy
01 July 2008
A 54-year-old woman patient presented with a 9-month history of early satiety and 10-kg weight loss. Six weeks before presentation the patient developed watery diarrhea, vomiting, alopecia, and dysgeu...
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Klaus Mönkemüller,
Helmut Neumann,
Matthias Evert
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Short communication
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page A26
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Foreign Body Reaction Mimicking Submucosal Tumor of the Colon
01 July 2008
A 47-year-old woman with a history of ulcerative colitis maintained on 2400 mg of mesalamine daily presented for an elective outpatient colonoscopy for dysplasia screening. She was mildly symptomatic ...
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Andrew I. Rackoff,
Patrick G. Brady
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Short communication
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page A30
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Recurrent Pancreatitis Caused By Displacement of the Major Duodenal Papilla
01 July 2008
A 55-year-old man was referred for endoscopy after his third bout of acute pancreatitis during a 6-month period. Imaging studies including abdominal computerized tomography and magnetic resonance chol...
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Mansour A. Parsi
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Short communication
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page A32
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Colon Cancer Diagnosed by Capsule Endoscopy
01 July 2008
A 46-year-old man presented with several intermittent episodes of melena and hematochezia. This necessitated hospital admission and work-up including a normal upper endoscopy, computed tomography scan...
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Samuel Giday,
Octavia Pickett–Blakely,
Gerard E. Mullin
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Short communication
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page A34
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Information for Readers
Correspondence regarding subscriptions or change of address should be directed to Clinical Gastroenterology and Hepatology, Elsevier, Periodicals Department, 6277 Sea Harbor Dr, Orlando, FL 32887-4800...
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Miscellaneous
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page A2
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Editorial Board
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Editorial board
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page A4
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Contents
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Contents list
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pages A7-A10
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Online Access Information
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Miscellaneous
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page A10
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Information for Authors
Clinical Gastroenterology and Hepatology publishes original papers, review articles, brief communications, and special category articles on all aspects of the digestive tract and the liver. Manuscript...
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Miscellaneous
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pages A17-A20
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Copyright Assignment, Authorship Responsibility, NIH Funding, Financial Disclosure, Institutional Review Board/Animal Care Committee Approval, and Sponsorship
In consideration of the American Gastroenterological Association (AGA) Institute (the “AGA Institute”) taking action to review and credit the below-identified submission (the “Manuscript”), and for ot...
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Miscellaneous
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page A25
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