| Electronic Images of the Month |
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Carcinoid Syndrome Unmasked by Fluoxetine, a Selective Serotonin Reuptake Inhibitor
11 July 2008
A 55-year-old man presented in 1995 with colicky abdominal pain, associated with bloating and borborygmi during a 6-month period. Clinical examination, routine blood tests, abdominal ultrasound scan, ...
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Rosanne M. Furse,
Caroline J. Green,
Anthony S. Mee
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Short communication
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pages e27-e28
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Pancreaticopleural Fistula Visualized by Multidetector Row Computed Tomography
A 75-year-old man visited our hospital complaining of dyspnea on working and abdominal fullness. He had consumed heavy alcohol daily for the past 40 years. Chest radiography showed bilateral pleural e...
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Terumi Kamisawa,
Naoko Kubota,
Tomomi Okamoto
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Short communication
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pages e29-e30
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Appendiceal Orifice Inflammation and Ulcerative Proctitis
A 14-year-old girl has a 2-month history of vague abdominal discomfort at the time of cheerleading and track activities. She reports hematochezia with the passage of formed to firm stools. Hemogram, e...
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Marian D. Pfefferkorn
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Short communication
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pages e31-e32
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| CME Activities |
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Exam 1: The Utility of Intraluminal Impedance in Patients With GERD-like Symptoms but Normal Endoscopy and 24-Hour pH Testing
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Miguel R. Arguedas
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Examination
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pages 835-836
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Exam 2: The Impact of Liver Disease, Alcohol Abuse, and Unintentional Ingestions on the Outcomes of Acetaminophen Overdose
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Miguel R. Arguedas
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Examination
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page 837
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| Abstracts From Around the World |
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Abstracts from Around the World
Corley DA, Kubo A, Levin TR, et al. Helicobacter pylori infection and the risk of Barrett's oesophagus: a community-based study. Gut 2008;57:727–733.
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Discussion
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pages 838-839
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| Editorial |
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Reflux Testing in the 21st Century: Is There a Role for pH Only?
01 July 2008
In November 2002, a group of international experts met in Porto, Portugal for the express purpose of critically evaluating the available techniques to measure gastroesophageal reflux (GER). The consen...
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Donald O. Castell
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Editorial
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pages 840-841
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| Review |
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Multidetector Computed Tomography During Combined Therapy for Pancreatic Adenocarcinoma
01 July 2008
By using experimental combined adjuvant and neoadjuvant therapies in pancreatic ductal adenocarcinoma patients, progress has been made in survival, clinical benefit response, and even downstaging of t...
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Desiree E. Morgan,
John C. Texada,
Cheri L. Canon,
Mark E. Lockhart,
James A. Posey,
Selwyn M. Vickers
et al.
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Review article
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pages 842-848.e3
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| Clinical Imaging |
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Imaging in Intestinal Ischemic Disorders
Intestinal ischemia and infarction are a heterogeneous group of diseases that have as their unifying theme hypoxia of the small bowel and/or colon. The incidence of bowel ischemia is increasing for a ...
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Richard M. Gore,
Kiran H. Thakrar,
Uday K. Mehta,
Jonathan Berlin,
Vahid Yaghmai,
Geraldine M. Newmark
et al.
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Full-length article
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pages 849-858
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| Education Practice |
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A Young Man With a New Diagnosis of Achalasia
06 May 2008
A 32-year-old man began to experience food sticking intermittently in the midchest about 2 years ago. By the time he presents to the gastroenterology clinic, he is complaining of dysphagia at every me...
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Joel E. Richter
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Full-length article
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pages 859-863
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| State of the Art |
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Insulin Resistance Among Patients With Chronic Hepatitis C: Etiology and Impact on Treatment
01 July 2008
Insulin resistance is extremely common and frequently is associated with comorbid conditions such as cardiovascular disease, hypertension, obesity, infertility, and neurodegeneration. In addition, ins...
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Stephen A. Harrison
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Full-length article
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pages 864-876
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| Endoscopy Corner |
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Large Sessile Adenomas Are Associated With a High Prevalence of Synchronous Advanced Adenomas
01 July 2008
Background & Aims: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain. Methods: We conducted a retrospective single-center review of synchronou...
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Wissam Mattar,
Douglas K. Rex
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Full-length article
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pages 877-879
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| Original Articles-Alimentary Tract |
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The Utility of Intraluminal Impedance in Patients With Gastroesophageal Reflux Disease–Like Symptoms But Normal Endoscopy and 24-Hour pH Testing
23 April 2008
Background & Aims: Fifty percent of patients with gastroesophageal reflux disease–like symptoms and negative endoscopy have negative 24-hour pH testing, suggesting that symptoms are not caused by ...
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Michael M. Kline,
Mark Ewing,
Nicole Simpson,
Loren Laine
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Full-length article
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pages 880-885
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Favorable Prognosis of Upper-Gastrointestinal Bleeding in 1041 Older Patients: Results of a Prospective Multicenter Study
05 June 2008
Background & Aims: Upper-gastrointestinal bleeding (UGIB) in the elderly is associated with high morbidity and mortality. The aims of this study were to determine the prognostic factors of UGIB in...
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Stéphane Nahon,
Olivier Nouel,
Herve Hagège,
Philippe Cassan,
Alexandre Pariente,
Remi Combes,
Alain Kerjean,
Sylva Doumet,
Perrine Cocq–Vezilier,
Guillaume Tielman,
Thierry Paupard,
Eric Janicki,
David Bernardini,
Michel Antoni,
Jajjia Haioun,
Didier Pillon,
Philippe Bretagnolle,
Groupe des Hémorragies Digestives Hautes de l'Association Nationale des Hépatogastroentérologues des Hôpitaux Généraux
et al.
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Full-length article
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pages 886-892
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Health Care Use in Patients With Chronic Intestinal Dysmotility Before and After Introducing a Specialized Day-Care Unit
05 June 2008
Background & Aims: Patients with chronic intestinal dysmotility (CID) have a lifelong disease, and no curative treatment is available. Interventions are needed to improve the care and support of t...
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Marie Iwarzon,
Ann Gardulf,
Greger Lindberg
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Full-length article
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pages 893-898
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Self-Administered Cognitive Behavior Therapy for Moderate to Severe Irritable Bowel Syndrome: Clinical Efficacy, Tolerability, Feasibility
05 June 2008
Background & Aims: Given the limitations of conventional therapies and restrictions imposed on newer pharmacologic agents, there is an urgent need to develop efficacious and efficient treatments t...
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Jeffrey M. Lackner,
James Jaccard,
Susan S. Krasner,
Leonard A. Katz,
Gregory D. Gudleski,
Kenneth Holroyd
et al.
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Full-length article
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pages 899-906
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Genetic Risk Factors in Young Patients With Ischemic Colitis
05 June 2008
Background & Aims: Although ischemic colitis (IC) usually occurs in old people with concomitant illnesses, an increasing frequency of this disease among young people has been reported. Inherited r...
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Angeliki Theodoropoulou,
Aekaterini Sfiridaki,
Pantelis Oustamanolakis,
Emanouel Vardas,
Aekaterini Livadiotaki,
Aekaterini Boumpaki,
Gregorios Paspatis,
Ioannis E. Koutroubakis
et al.
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Full-length article
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pages 907-911
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Nonmedical Costs of Colorectal Cancer Screening With the Fecal Occult Blood Test and Colonoscopy
06 June 2008
Background & Aims: The nonmedical costs of colorectal cancer screening are unknown. However, they might influence screening uptake and impact the cost-effectiveness of colorectal cancer screening ...
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Steven J. Heitman,
Flora Au,
Braden J. Manns,
S. Elizabeth McGregor,
Robert J. Hilsden
et al.
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Full-length article
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pages 912-917.e1
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| Original Articles-Liver, Pancreas, and Biliary Tract |
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Impact of Liver Disease, Alcohol Abuse, and Unintentional Ingestions on the Outcomes of Acetaminophen Overdose
20 May 2008
Background & Aims: Acetaminophen overdose is the most common cause of acute liver failure in the U.S. and other Western countries. Unintentional overdoses, alcohol abuse, and underlying liver dise...
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Robert P. Myers,
Abdel Aziz M. Shaheen,
Bing Li,
Stafford Dean,
Hude Quan
et al.
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Full-length article
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pages 918-925
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Regression of Hepatic Fibrosis After Intestinal Transplantation in Total Parenteral Nutrition Liver Disease
Background & Aims: Hepatic fibrosis may occur in patients with intestinal failure requiring total parenteral nutrition, leading to liver dysfunction necessitating combined intestinal and liver tra...
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M. Isabel Fiel,
Bernhard Sauter,
Hai–Shan Wu,
Gonzalo Rodriguez–Laiz,
Gabriel Gondolesi,
Kishore Iyer,
Thomas D. Schiano
et al.
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Full-length article
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pages 926-933
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Accuracy of Family History of Hemochromatosis or Iron Overload: The Hemochromatosis and Iron Overload Screening Study
01 July 2008
Background & Aims: The aim of this study was to assess the analytic validity of self-reported family history of hemochromatosis or iron overload. Methods: A total of 141 probands, 549 family membe...
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Ronald T. Acton,
James C. Barton,
Leah V. Passmore,
Paul C. Adams,
Gordon D. Mclaren,
Catherine Leiendecker–Foster,
Mark R. Speechley,
Emily L. Harris,
Oswaldo Castro,
Jacob A. Reiss,
Beverly M. Snively,
Barbara W. Harrison,
Christine E. Mclaren
et al.
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Full-length article
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pages 934-938
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Increased Risk of Primary Sclerosing Cholangitis and Ulcerative Colitis in First-Degree Relatives of Patients With Primary Sclerosing Cholangitis
Background & Aims: The importance of genetic factors for the development of primary sclerosing cholangitis (PSC) is incompletely understood. This study assessed the risk of PSC and inflammatory bo...
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Annika Bergquist,
Scott M. Montgomery,
Shahram Bahmanyar,
Rolf Olsson,
Åke Danielsson,
Stefan Lindgren,
Hanne Prytz,
Rolf Hultcrantz,
Lars Lööf,
Hanna Sandberg–Gertzén,
Sven Almer,
Johan Askling,
Anna Ehlin,
Anders Ekbom
et al.
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Full-length article
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pages 939-943
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Endoscopic or Percutaneous Biliary Drainage for Gallbladder Cancer: A Randomized Trial and Quality of Life Assessment
01 July 2008
Background & Aims: Patients with carcinoma of the gallbladder (GBC) and obstructive jaundice are usually not amenable to curative resection. Effective palliation by biliary decompression is the go...
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Sundeep Singh Saluja,
Manpreet Gulati,
Pramod Kumar Garg,
Hemraj Pal,
Sujoy Pal,
Peush Sahni,
Tushar K. Chattopadhyay
et al.
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Full-length article
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pages 944-950.e3
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| Letters to the Editor |
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Risk of Pancreatitis in Patients With Celiac Disease: Is Autoimmune Pancreatitis a Biologically Plausible Mechanism?
We read with interest the study by Ludvigsson et al. By using an epidemiologic database the authors described that patients with celiac disease (CD) had an increased risk of both acute pancreatitis (h...
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John S. Leeds,
David S. Sanders
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Correspondence
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page 951
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Reply
Leeds and Sanders present interesting data on CD and exocrine pancreatic insufficiency (EPI). Their report of a positive association between CD and pancreatic disease is consistent with our findings. ...
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Jonas F. Ludvigsson,
Scott M. Montgomery,
Anders Ekbom
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Correspondence
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page 951
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Cover
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Miscellaneous
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page OFC
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| Frontmatter |
| Images of the Month |
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Author(s) |
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Exudative Hemorrhagic Duodenitis as a Primary Event in a Child With Henoch-Schönlein Purpura
14 April 2008
A 4-year-old girl had a history of an acute onset of severe generalized colicky abdominal pain, fever, oral ulcer, bloody diarrhea, and melena for 7 days. An examination showed fever, and generalized ...
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Wikrom Karnsakul,
Kenneth B. Fallon,
Stephany Swart
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Short communication
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page A24
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Minimal-Change Esophagitis on Narrow-Band Imaging
05 June 2008
A 45-year-old man presented with a 1-month history of recurrent episodes of heartburn, regurgitation, and reflux symptoms. His physical examination was normal.
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Rupa Banerjee,
D. Nageshwar Reddy
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Short communication
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pages A26-A26.e2
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Giant Appendiceal Mucocele
03 June 2008
A 68-year-old man presented for screening colonoscopy. His past medical history included hypertension but was otherwise unremarkable. On endoscopy, a large presumably submucosal tumor was seen in the ...
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Franz Ludwig Dumoulin,
Thomas Berns,
Robin Sen Gupta
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Short communication
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page A30
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Whipple's Disease
21 May 2008
A 51-year-old man presented with migratory arthritis involving the knees, wrists, and elbows and weight loss of 15 kg during a 12-month period. The patient was treated with a combination of NSAIDs and...
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Helmut Neumann,
Klaus Mönkemüller,
Peter Malfertheiner
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Short communication
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page A32
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Information for Readers
Correspondence regarding subscriptions or change of address should be directed to Clinical Gastroenterology and Hepatology, Elsevier, Periodicals Department, 6277 Sea Harbor Dr, Orlando, FL 32887-4800...
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Miscellaneous
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page A2
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Editorial Board
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Editorial board
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page A4
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Contents
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Contents list
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pages A7-A10
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Online Access Information
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Miscellaneous
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page A10
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Information for Authors
Clinical Gastroenterology and Hepatology publishes original papers, review articles, brief communications, and special category articles on all aspects of the digestive tract and the liver. Manuscript...
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Miscellaneous
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pages A17-A20
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Copyright Assignment, Authorship Responsibility, NIH Funding, Financial Disclosure, Institutional Review Board/Animal Care Committee Approval, and Sponsorship
In consideration of the American Gastroenterological Association (AGA) Institute (the “AGA Institute”) taking action to review and credit the below-identified submission (the “Manuscript”), and for ot...
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Miscellaneous
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page A22
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