| Electronic Images of the Month |
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Spontaneous Intramural Esophageal Hematoma in Association With Idiopathic Thrombocytopenic Purpura: A Cause of Non-Cardiac Chest Pain
04 March 2010
An 81-year-old man presented to the Emergency Department with severe acute onset epigastric and retrosternal chest discomfort with dysphagia coincident with the consumption of a small meal. His medica...
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Ted Xenodemetropoulos,
Khurram J. Khan,
Premsyl Bercik
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Short communication
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pages e73-e74
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Pancreatic Endocrine Carcinoma Protruding From the Major Papilla
08 February 2010
A 33-year-old man presented with obstructive jaundice and fever. Duodenoscopy revealed a tumor protruding from the papilla of Vater (A). However, biopsy specimens showed only necrotic tissue. Abdomina...
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Junko Umeda,
Takao Itoi,
Nobuhito Ikeuchi
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Short communication
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pages e75-e76
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Chest Wall Hematoma After Percutaneous Liver Biopsy
12 March 2010
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Chaorui Tian,
Michael D. Sitrin,
Sam J. Samuel
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Short communication
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page e77
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| CME Activities |
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Article Title |
Author(s) |
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Exam 1: Low-Dose Maintenance Therapy With Infliximab Prevents Postsurgical Recurrence of Crohn's Disease
10 May 2010
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C. Mel Wilcox
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Examination
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pages e78-e79
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Exam 2: Incidence and Prognosis of the Different Types of Functional Renal Failure in Cirrhotic Patients With Ascites
10 May 2010
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C. Mel Wilcox
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Examination
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page e80
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| Abstracts From Around the World |
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Abstracts from Around the World
07 June 2010
A common dilemma in the management of Crohn's disease is the patient who either cannot be discontinued from steroids because of continued disease activity or previously responded and now, within a sho...
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Discussion
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pages 553-555
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| Editorial |
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Anti–Tumor Necrosis Factor Therapy in Crohn's Disease: More Information and More Questions About the Long Term
26 April 2010
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Charles N. Bernstein
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Editorial
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pages 556-558
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| Review |
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Health-Related Quality of Life in Patients With Hepatocellular Carcinoma: A Systematic Review
22 March 2010
Background & Aims: This systematic review was conducted to identify the following: (1) generic and disease-specific measures used to assess health-related quality of life (HRQOL) in patients with ...
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Sheng–Yu Fan,
Christine Eiser,
Ming–Chih Ho
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Review article
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pages 559-564.e10
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| Education Practice |
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A 52-Year-Old Man With Heartburn: Should He Undergo Screening for Barrett's Esophagus?
30 November 2009
A 52-year-old man is referred to your gastroenterology practice for a history of gastroesophageal reflux disease (GERD). The patient reports a long history of heartburn symptoms, dating back at least ...
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Seth D. Crockett,
A. Sidney Barritt,
Nicholas J. Shaheen
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Full-length article
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pages 565-571
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| Endoscopy Corner |
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Author(s) |
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Spiral Enteroscopy Is Safe and Effective for an Elderly United States Population of Patients With Numerous Comorbidities
26 April 2010
Background & Aims: Preliminary studies performed outside of the United States demonstrated that spiral enteroscopy is safe and effective when performed in young, healthy patients. However, spiral ...
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Joel R. Judah,
Peter V. Draganov,
Yvette Lam,
Wei Hou,
Jonathan M. Buscaglia
et al.
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Full-length article
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pages 572-576
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| Practice Management: Opportunities and Challenges |
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Author(s) |
Type |
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The Study of a Contaminated Colonoscope
Gastrointestinal (GI) endoscopy departments may sample their flexible endoscopes microbiologically, either after reprocessing or prolonged storage, as part of a comprehensive quality assurance program...
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Lawrence F. Muscarella
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Full-length article
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pages 577-580.e1
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| Original Articles—Alimentary Tract |
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Author(s) |
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Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption
12 April 2010
Background & Aims: Symptomatic lactose intolerance is common; however, abdominal symptoms that patients experience after ingestion of lactose-containing foods can have causes beyond lactose malabs...
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Francesc Casellas,
Anna Aparici,
Maite Casaus,
Purificación Rodríguez,
Juan R. Malagelada
et al.
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Full-length article
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pages 581-586
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Celiac Crisis Is a Rare but Serious Complication of Celiac Disease in Adults
26 April 2010
Background & Aims: Celiac crisis is a life-threatening syndrome in which patients with celiac disease have profuse diarrhea and severe metabolic disturbances. Celiac crisis is rare among adults an...
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Shailaja Jamma,
Alberto Rubio–Tapia,
Ciaran P. Kelly,
Joseph Murray,
Robert Najarian,
Sunil Sheth,
Detlef Schuppan,
Melinda Dennis,
Daniel A. Leffler
et al.
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Full-length article
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pages 587-590
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Low-Dose Maintenance Therapy With Infliximab Prevents Postsurgical Recurrence of Crohn's Disease
08 February 2010
Background & Aims: Infliximab might prevent postsurgical recurrence of Crohn's disease. However, it is unclear whether long-term therapy is necessary and whether alternative strategies could be ap...
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Dario Sorrentino,
Alberto Paviotti,
Giovanni Terrosu,
Claudio Avellini,
Marco Geraci,
Dimitra Zarifi
et al.
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Full-length article
  
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pages 591-599.e1
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Continuous Therapy With Certolizumab Pegol Maintains Remission of Patients With Crohn's Disease for up to 18 Months
01 February 2010
Background & Aims: The safety and efficacy of maintenance therapy with the anti–tumor necrosis factor certolizumab pegol has not been reported beyond 6 months. We assessed the long-term efficacy, ...
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Gary R. Lichtenstein,
Ole Ø. Thomsen,
Stefan Schreiber,
Ian C. Lawrance,
Stephen B. Hanauer,
Ralph Bloomfield,
William J. Sandborn,
Precise 3 Study Investigators
et al.
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Full-length article

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pages 600-609
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Low Rates of Cancer or High-Grade Dysplasia in Colorectal Polyps Collected From Computed Tomography Colonography Screening
22 March 2010
Background & Aims: In patients with polyps detected at computed tomography colonography (CTC) screening, management decisions are influenced by the likelihood of important polyp histology. We asse...
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Perry J. Pickhardt,
Kendra S. Hain,
David H. Kim,
Cesare Hassan
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Full-length article
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pages 610-615
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| Original Articles—Liver, Pancreas, and Biliary Tract |
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Author(s) |
Type |
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Incidence and Prognosis of Different Types of Functional Renal Failure in Cirrhotic Patients With Ascites
19 April 2010
Background & Aims: Hepatorenal syndrome is a well-characterized type of terminal renal failure that occurs in patients with cirrhosis with ascites. Information about other types of functional rena...
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Silvia Montoliu,
Belén Ballesté,
Ramon Planas,
Marco Antonio Álvarez,
Mònica Rivera,
Mireia Miquel,
Helena Masnou,
Isabel Cirera,
Rosa Maria Morillas,
Susanna Coll,
Margarita Sala,
Montserrat García–Retortillo,
Nuria Cañete,
Ricard Solà
et al.
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Full-length article
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pages 616-622
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Spontaneous Bacterial Peritonitis Before Liver Transplantation Does Not Affect Patient Survival
26 April 2010
Background & Aims: Spontaneous bacterial peritonitis (SBP) is a devastating complication of cirrhosis with high mortality. The impact of a prior episode of SBP on the outcome of liver transplantat...
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Rawad Mounzer,
Shahid M. Malik,
John Nasr,
Bahar Madani,
Michael E. Devera,
Jawad Ahmad
et al.
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Full-length article
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pages 623-628.e1
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Contrast Harmonic Echo–Endoscopic Ultrasound Improves Accuracy in Diagnosis of Solid Pancreatic Masses
26 April 2010
Background & Aims: Contrast harmonic echo (CHE) has been developed for endoscopic ultrasound (EUS). This new technique detects echo signals from microbubbles in vessels with very slow flow, withou...
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Pietro Fusaroli,
Alessia Spada,
Maria Grazia Mancino,
Giancarlo Caletti
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Full-length article
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pages 629-634.e2
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| Brief Communication |
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Detective Work in Drug-Induced Liver Injury: Sometimes It Is All About Interviewing the Right Witness
05 April 2010
Diagnosing drug-induced liver injury (DILI) relies primarily on history taking. We report 4 cases in which DILI was missed or the drug was misidentified when physicians relied solely on patient histor...
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A. Sidney Barritt,
Joseph Lee,
Paul H. Hayashi
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Full-length article
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pages 635-637
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| Letters to the Editor |
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Author(s) |
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Reflux Is Unlikely to Occur During Stable Sleep
07 January 2010
Regrettably, the article by Gagliardi et al in the September 2009 issue of Clinical Gastroenterology and Hepatology inappropriately reinforces, both in its title and in its contents, the unproven asse...
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John Dent
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Correspondence
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pages 638-639
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Reply
14 May 2010
The comments of Professor Dent are greatly appreciated. Our current study did not measure transient lower esophageal sphincter relaxation, only esophageal pH. In all cases, acid reflux events preceded...
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Anthony J. Dimarino,
Sidney Cohen
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Correspondence
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page 639
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Prevalence, Diagnosis, and Profile of Autoimmune Pancreatitis Presenting With Features of Acute or Chronic Pancreatitis
02 March 2010
The article by Sah et al in the January edition of Clinical Gastroenterology and Hepatology is an outstanding overview of a large series of patients with autoimmune pancreatitis (AIP). I find it inter...
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Khurram J. Khan
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Correspondence
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pages 639-640
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Reply
05 May 2010
We highly appreciate Dr Khan's response and questions about monitoring serum immunoglobulin G (IgG) 4 levels in autoimmune pancreatitis (AIP) patients. This is an important issue with significant impl...
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Raghuwansh Sah,
Suresh T. Chari
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Correspondence
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pages 640-641
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Cover
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Miscellaneous
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page OFC
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| Frontmatter |
| Images of the Month |
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Article Title |
Author(s) |
Type |
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Esophageal Intramural Pseudodiverticulosis: A Rare Cause of Esophageal Stricture
25 December 2009
A 60-year-old man with diabetes and alcohol dependence had difficulty swallowing and was referred to our hospital. Barium esophagography showed a stricture of the thoracic esophagus with multiple smal...
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Shunsuke Yamamoto,
Shusaku Tsutsui,
Norio Hayashi
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Short communication
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page A28
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Gastrojejunocolic Fistula Overlooked as an Ulcer in Endoscopy
25 December 2009
A 72-year-old man, receiving subtotal gastrectomy for peptic ulcer disease 20 years ago, complained of diarrhea for 1 month before admission. Loose stool passage occurred after each meal and undigeste...
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Pin–Chao Wang,
Chih–Hsin Lee,
Chia–Chi Wang
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Short communication
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page A32
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Tension Hemothorax: A Dreaded Complication of Percutaneous Liver Biopsy
08 February 2010
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Ka–Ho Lok,
Hon–Da Au,
Kin–Kong Li
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Short communication
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page A36
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Editorial Board
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Editorial board
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page A4
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Contents
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Contents list
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pages A9-A12
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Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute br...
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Miscellaneous
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pages A15-A16
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Copyright Assignment, Authorship Responsibility, NIH Funding, Financial Disclosure, Institutional Review Board/Animal Care Committee Approval, and Sponsorship
In consideration of the American Gastroenterological Association (AGA) Institute (the “AGA Institute”) taking action to review and credit the below-identified submission (the “Manuscript”), and for ot...
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Miscellaneous
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page A18
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Information for Authors
Clinical Gastroenterology and Hepatology publishes clinical articles on all aspects of the digestive system, including the liver and pancreas. The types of articles Clinical Gastroenterology and Hepat...
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Miscellaneous
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pages A19-A26
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