Efficacy of Esophageal Impedance/Ph Monitoring in Patients With Refractory Gastroesophageal Reflux Disease, on and off Therapy

In July 2009 Pritchett et al compared impedance/pH (MII-pH) on-therapy with 48-hour wireless pH-monitoring off-therapy in those refractory to proton pump inhibitors (PPIs). They conclude MII-pH on-therapy might provide the single best strategy for evaluation of persistent reflux.