Clinical Gastroenterology and Hepatology
Volume 7, Issue 4 , Pages 397-414, April 2009

Hepatitis C Virus: A Critical Appraisal of Approaches to Therapy

  • David R. Nelson

      Affiliations

    • Hepatology and Liver Transplantation, University of Florida, Gainesville, Florida
    • Corresponding Author InformationReprint requests Address requests for reprints to: David Nelson, MD, Chair, Professor of Medicine, Director, Hepatology and Liver Transplantation, University of Florida, 1600 SW Archer Road, Room M440, Medical Science Building, Gainesville, Florida 32610; fax: (352) 392-7393
    • ,
  • Gary L. Davis

      Affiliations

    • Baylor University Medical Center, Dallas, Texas
    • ,
  • Ira Jacobson

      Affiliations

    • Division of Gastroenterology & Hepatology, Weill Cornell Medical College, New York, New York
    • ,
  • Gregory T. Everson

      Affiliations

    • Department of Hepatology, University of Colorado Health Sciences Center, Aurora, Colorado
    • ,
  • Michael W. Fried

      Affiliations

    • Department of Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    • ,
  • Stephen A. Harrison

      Affiliations

    • Department of Hepatology, Brooke Army Medical Center, San Antonio, Texas
    • ,
  • Tarek Hassanein

      Affiliations

    • Department of Medicine and Surgery, University of California San Diego, San Diego, California
    • ,
  • Donald M. Jensen

      Affiliations

    • Department of Medicine, University of Chicago Medical Center, Chicago, Illinois
    • ,
  • Karen L. Lindsay

      Affiliations

    • Hepatitis Research and Treatment Center, University of Southern California, Los Angeles, California
    • ,
  • Norah Terrault

      Affiliations

    • Department of Medicine, University of California, San Francisco, San Francisco, California
    • ,
  • Nizar Zein

      Affiliations

    • Department of Hepatology and Transplantation, Cleveland Clinic, Cleveland, Ohio

published online 25 November 2008.

See related article, Dahari H et al, on page 1402 in Gastroenterology.

See CME exam on page 366.

Abbreviations used in this paper: AFP, alpha fetoprotein, AGA, American Gastroenterological Association, ALT, alanine aminotransferase, APRI, aspartate aminotransferase platelet ratio index, AUROC, area under the receiver operator characteristics, CI, confidence interval, CT, computed tomography, EPO, erythropoietin, ESA, erythropoiesis-stimulating agents, HALT-C, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, HCC, hepatocellular cancer, HCV, hepatitis C virus, HIV, human immunodeficiency virus, HVL, high viral load, IFN, interferon, MRA, magnetic resonance angiography, MRI, magnetic resonance imaging, MU, million units, PEG, pegylated, RBV, ribavirin, RVR, rapid virologic response, SVR, sustained virologic response

 

 This article has an accompanying continuing medical education activity on page 366. Learning Objective—At the end of this activity the learner should identify factors that are important in the treatment and management of a patient with chronic hepatitis C.

 Conflicts of interest The authors disclose the following: the HCV Council meeting was supported by an educational grant from Roche Pharmaceuticals.

PII: S1542-3565(08)01160-9

doi:10.1016/j.cgh.2008.11.016

Refers to article:

  • Exam 1: Hepatitis C Virus: A Critical Appraisal of Approaches to Therapy , 27 February 2009

    Joseph R. Bloomer
    Clinical Gastroenterology and Hepatology April 2009 (Vol. 7, Issue 4, Pages 365-366)

Clinical Gastroenterology and Hepatology
Volume 7, Issue 4 , Pages 397-414, April 2009