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See related article, Dahari H et al, on page 1402 in Gastroenterology. See CME exam on page 366. Abbreviations used in this paper: AFP, alpha fetoprotein, AGA, American Gastroenterological Association, ALT, alanine aminotransferase, APRI, aspartate aminotransferase platelet ratio index, AUROC, area under the receiver operator characteristics, CI, confidence interval, CT, computed tomography, EPO, erythropoietin, ESA, erythropoiesis-stimulating agents, HALT-C, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, HCC, hepatocellular cancer, HCV, hepatitis C virus, HIV, human immunodeficiency virus, HVL, high viral load, IFN, interferon, MRA, magnetic resonance angiography, MRI, magnetic resonance imaging, MU, million units, PEG, pegylated, RBV, ribavirin, RVR, rapid virologic response, SVR, sustained virologic response ⁎ Hepatology and Liver Transplantation, University of Florida, Gainesville, Florida ‡ Baylor University Medical Center, Dallas, Texas § Department of Hepatology, University of Colorado Health Sciences Center, Aurora, Colorado ∥ Department of Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina ¶ Department of Hepatology, Brooke Army Medical Center, San Antonio, Texas # Department of Medicine and Surgery, University of California San Diego, San Diego, California ⁎⁎ Division of Gastroenterology & Hepatology, Weill Cornell Medical College, New York, New York ‡‡ Department of Medicine, University of Chicago Medical Center, Chicago, Illinois §§ Hepatitis Research and Treatment Center, University of Southern California, Los Angeles, California ∥∥ Department of Medicine, University of California, San Francisco, San Francisco, California ¶¶ Department of Hepatology and Transplantation, Cleveland Clinic, Cleveland, Ohio
This article has an accompanying continuing medical education activity on page 366. Learning Objective—At the end of this activity the learner should identify factors that are important in the treatment and management of a patient with chronic hepatitis C. Conflicts of interest The authors disclose the following: the HCV Council meeting was supported by an educational grant from Roche Pharmaceuticals. PII: S1542-3565(08)01160-9 doi:10.1016/j.cgh.2008.11.016 © 2009 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Hepatitis C Virus: A Critical Appraisal of Approaches to Therapy