Current Issue February 2012, Vol. 10, No. 2
Editor's Essential Reading
Original Articles—Liver, Pancreas, and Biliary Tract
Factors Related to Fatigue in Patients With Cirrhosis Before and After Liver Transplantation 
Fatigue is common among patients with cirrhosis and associated with impaired quality of life. Psychological distress, severity of cirrhosis, and low levels of cortisol determine general fatigue, whereas anemia and impaired renal function also contribute to physical fatigue. Physical fatigue remains of concern for patients who have received liver transplants for cirrhosis.
Issue Highlights
Endoscopy Corner
Colonoscopy With Clipping Is Useful in the Diagnosis and Treatment of Diverticular BleedingColonoscopy can be a safe first-line diagnostic and therapeutic approach for patients with severe LGIB. Endoscopic clipping provides hemostasis of active diverticular bleeding. Recurrent bleeding occurs in about 21% of patients who were treated with clips, at approximately 4 years; most bleeding is self-limited or can be retreated by endoscopic clipping.
Brief Communication
- The Zollinger-Ellison Syndrome: Dangers and Consequences of Interrupting Antisecretory Treatment
PPI treatment interruption has dangerous consequences, and PPI therapy always should be maintained in patients known or suspected of ZES. Diagnostic evaluations should be performed under PPI protection.
Original Articles—Alimentary Tract
Travel-Associated Health Risks for Patients With Inflammatory Bowel DiseasePatients with IBD have a higher rate of illness compared with controls during trips to industrialized countries, but not to developing or tropical regions. These findings indicate that most travel-associated illnesses stem from sporadic IBD flares rather than increased susceptibility to enteric infections.
Original Articles—Liver, Pancreas, and Biliary Tract
Histologic and Imaging Features of Mural Nodules in Mucinous Pancreatic Cysts Malignancy is associated with epithelial nodules in BD-IPMNs and MCNs, but most echogenic lesions detected in cysts by EUS are mucus. Knowledge of features that discriminate mucus from mural nodules improves the diagnostic accuracy of EUS.
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Discussion19 January 2012
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Increased Risk of Death From Iron Overload Among 422 Treated Probands With HFE Hemochromatosis and Serum Levels of Ferritin Above 1000 Milligrams/Liter at Diagnosis19 January 2012
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Endoscopic Therapy is Effective for Patients with Chronic Pancreatitis16 January 2012
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Erosive Reflux Disease Increases Risk for Esophageal Adenocarcinoma Risk, Compared With Nonerosive Reflux16 January 2012
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Progressive Primary Sclerosing Cholangitis Requiring Liver Transplantation Is Associated With Reduced Need For Colectomy In Patients With Ulcerative Colitis16 January 2012
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Independent Association Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in a US Population Study16 January 2012
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CME Activities–Exams 1 2012-0313 January 2012
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Exam 2: Risks for Colorectal Neoplasia in Patients With Colonic Crohn's Disease and Concomitant Primary Sclerosing Cholangitis13 January 2012
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A Predictive Model Identifies Patients Most Likely to Have Inadequate Bowel Preparation for Colonoscopy11 January 2012
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Ectopic Thyroid Presenting As A Liver Mass10 January 2012


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